The latest issue of “Journal of the American Chemical Society” published a research article entitled with “Shape Complementarity Modulated Self-assembly of Nanoring and Nanosphere Hetero-nanostructures” (J. Am. Chem. Soc. 2020, DOI: 10.1021/jacs.0c04678)，which is accomplished by the research teams led by Prof. Baoquan Ding from the National Center for Nanoscience and Technology (NCNST), and Prof. Zhihong Nie from Fudan University. This work provides a new shape-based self-assembly rules for organizing shaped nanoparticles, and precisely assembled nanorings and nanospheres into discrete hybrid nanostructures with defined morphologies and high yield.
For molecular recognition, shape complementarity is essential in various events, such as host-guest molecular systems, enzymatic reactions, and target binding by aptamers. Similarly, the shape of nanoparticles (NPs) can strongly influence the interactions between NPs, thus determining the orientation and the assembled structures of NPs, and affecting the properties of the assemblies. Shape recognition has been rarely adopted in the self-assembly of colloidal particles, especially in the case of NPs with different shapes, largely due to the challenge in synthesizing of colloidal building blocks with shape complementarity. Nevertheless, there is an urgent need for the development of new shape-based self-assembly rules for organizing shaped NPs including gold nanorings (AuNRs).
In recent years, Prof. Ding’s group has been focusing on the study of fabricating metal and metal oxide patterns (J. Am. Chem. Soc. 2019,141, 17968) as well as assembling metal nanoparticles with prescribed nanostructures (Angew. Chem. Int. Ed., 2018, 57, 2846; Nano Lett., 2017, 17, 7125) on DNA origami. Based on these researches, Prof. Ding’s group cooperated with Prof. Nie’s group, proposing a novel shape complementarity-based strategy for DNA guided self-assembly of gold nanoring-based heterostructures (AuNR-HNs). This work reported a simple, yet powerful strategy for fabricating AuNR-HNs with well-defined geometries and high yield. The assembly of various geometries of AuNR-HNs is driven by the sequence recognition of DNA ligands between the nanoparticles, and the shape complementarity between AuNRs and AuNSs dictates the morphology of the assembled structures. Experimental evidence of dark quadrupolar ring mode excitation in AuNR-HNs are also presented through single-particle optical measurements. This strategy can potentially extend to other NP combinations with shape complementarity, and will be beneficial in the study of nanoparticle assembly, photonic element interaction and the development of plasmon-based optical devices.
Associate Prof. Na Li from NCNST is the first author of this work, Prof. Baoquan Ding from NCNST and Prof. Zhihong Nie from Fudan University are the corresponding authors. This work was supported by the National Natural Science Foundations of China, National Basic Research Programs of China, the Key Research Program of Frontier Sciences, CAS, the K. C. Wong Education Foundation, Beijing Municipal Science & Technology Commission and the Strategic Priority Research Program of Chinese Academy of Sciences (B).
Click on the link below to see the original articles: https://pubs.acs.org/doi/10.1021/jacs.0c04678.
Figure 1. Schematic illustration of shape complementarity modulated assembly of AuNRs and AuNSs functionalized with complementary DNA strands into discrete hybrid plasmonic nanostructures with defined morphologies.
Figure 2. Representative TEM and SEM images of Saturn-like structures, diamond-ring shaped structures and bowknot-like structures assembled by DNA.