National Center for Nanoscience and Technology, China

Faculty

Xiao ZHAO

Title：	Professor
E-mail：	zhaox@nanoctr.cn
Affiliation：	National Center for Nanoscience and Technology (NCNST) No.11 Beiyitiao Zhongguancun, 100190 Beijing, P. R. China
Group Webpage：

Education and Professional Experience:

2019.9-now Professor, National center for nanoscience and technology (NCNST)

2016.8-2019.9 Postdoctor, National center for nanoscience and technology (NCNST), China

2013.9-2016.6 Ph.D. major in Oncology, Tianjin medical university, China

2010.9-2013.6 M.S. major in Oncology, Tianjin medical university, China

2005.9-2010.6 B.S. major in Clinical Medicine, Henan university, China

Research Interests:

Research Interests

1. Nano-drug design and synthesis for the clinical treatment of cancer.

2. mRNA-delivery nanomaterials and their applications.

3. Biogenic nanoparticles and their application in tumor therapy.

Selected Publications (full list via Researchgate)

1. Yao Li#, Xiao Zhao#, Xiaoli Liu#, et al. A Bioinspired Nanoprobe with Multilevel Responsive T1 -Weighted MR Signal-Amplification Illuminates Ultrasmall Metastases. Advanced Materials 2020, 32: e1906799.

2. Guangna Liu#, Xiao Zhao#, et al. Engineering Biomimetic Platesomes for pH-Responsive Drug Delivery and Enhanced Anti-Tumor Activity. Advanced Materials 2019, 31(32): e1900795.

3. Shaoli Liu#, Yinlong Zhang#, Xiao Zhao#, et al. Tumor-specific silencing of tissue factor suppresses metastasis and prevents cancer-associated hypercoagulability. Nano Letters 2019, 19(7): 4721-4730.

4. Xiao-Li Liu#, Jianjun Zheng#, Wei Sun#, Xiao Zhao#, et al. Ferrimagnetic Vortex Nanorings-Mediated Mild Magnetic Hyperthermia Imparts Potent Immunological Effect for Treating Cancer Metastasis. ACS Nano 2019, 13(8): 8811-8825.

5. Jiayan Lang#, Xiao Zhao#, et al. Reshaping Prostate Tumor Microenvironment To Suppress Metastasis via Cancer-Associated Fibroblast Inactivation with Peptide-Assembly-Based Nanosystem. ACS Nano 2019, 13(11): 12357-12371.

6. Xiao Zhao, Liang Liu, et al. A CRISPR-Cas13a system for efficient and specific therapeutic targeting of mutant KRAS for pancreatic cancer treatment. Cancer Letters 2018, 431: 171-181.

7. Xiao Zhao, Xiuchao Wang, et al. Precision design of nanomedicines to restore gemcitabine chemosensitivity for personalized pancreatic ductal adenocarcinoma treatment. Biomaterials 2018, 158: 44-55.

8. Xiao Zhao, Xiuchao Wang, et al. A combinatorial strategy using YAP and pan-RAF inhibitors for treating KRAS-mutant pancreatic cancer. Cancer Letters 2017, 402: 61-70.

9. Xiao Zhao, Keni Yang, et al. Inducing Enhanced Immunogenic Cell Death with Nanocarrier-based Drug Delivery Systems for Pancreatic Cancer, Biomaterials 2016, 102: 187-197.

10. Feng Li#, Xiao Zhao#, et al. Multiple Layer-by-Layer Lipid-Polymer Hybrid Nanoparticles for Improved FOLFIRINOX Chemotherapy in Pancreatic Tumor Models, Advanced Functional Materials 2015, 25(5): 788-798.

11. Xiao Zhao, Song Gao, et al. Hypoxia-Inducible Factor-1 Promotes Pancreatic Ductal Adenocarcinoma Invasion and Metastasis by Activating Transcription of the Actin-Bundling Protein Fascin, Cancer Research 2014, 74(9): 2455-2464.