The research explores the use of metal elements to modulate gut microbiota and maintain gut health. Tungsten and zinc, key metal elements, have shown potential in regulating gut bacteria and allevi...2025-04-02
We developed cRGD-NP@A, a polymeric nanomedicine that selectively targets and destroys tumor-related platelets (TAPs). By breaking the connection between platelets and tumors and reducing immune-su...2025-03-10
We achieve a ∼438-fold exciton photoluminescence enhancement by constructing a Fabry-Pérot cavity consisting of monolayer WS2 and a micron-scale hole on the SiO2/Si substrate. The overall enhance...2025-02-21
Deep brain stimulation (DBS) technology enables the neural modulation with precise spatial control, but requires permanent implantation of conduits. Here, we describe a photothermal wireless DBS na...2025-01-16
We developed a universal preventive tumor nanovaccine and identified multiple tumor-shared antigenic peptides associated with immunogenicity. The nanovaccine demonstrated good safety, stimulated si...2024-12-28
We demonstrated a tumor membrane antigens-based nanovaccine derived from liposomal doxorubicin treated tumor tissues, which is efficacious in inducing a potent immunological defense against multipl...2024-12-24
We present an mRNA compartmentalization–based cancer vaccine, comprising a multi-module DNA nanostructure (MMDNS)–assembled compartment for efficient mRNA translation and adjuvant efficiency. The...2024-11-23
We have developed a reinforcement learning-based enhanced sampling method, known as Adaptive CVgen, which enables simultaneous exploration of both short- and long-range dynamic behaviors during sys...2024-10-31
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