National Center for Nanoscience and Technology, China

Faculty

Dong HAN

Title：	Professor
E-mail：	dhan@nanoctr.cn
Affiliation：	National Center for Nanoscience and Technology (NCNST) No.11 Beiyitiao Zhongguancun, 100190 Beijing, P. R. China
Group Webpage：	https://nanoctr.cas.cn/handong/

Education and Professional Experience:

He was graduated from Beijing University of Chinese Medicine and served as a clinic doctor for seven years in Department of Hemotology, Xi Yuan Hospital. He received his clinical M.S. degree (1998, 07) and M.D/-PhD (2001, 07) from the China Academy of Chinese Medical Sciences and then worked as a postdoctoral fellow in the Department of Physics, Tsinghua University. Research visitor scholar in Hong Kong Baptist University (2003, 07-09); Senior research visitor scholar at the Department of Chemistry in Ecole Normale Supérieure (ENS) (2005, 07-10) and Biodesign Institute in Arizona State University (2013, 09-11).

In 2004, he joined the National Center for Nanoscience and Technology of China (NCNST), where he directed researches for biological imaging and nanomedicine with a focus on nano-imaging, functional biointerfaces and soft matter of medicine. Recently, he found a green pathway in the living system based on confined mass transportation, namely interstitial stream, suggesting a new life model of "living hierarchical complex fluid—interstitial stream". Then he proposed a new medical model, that is, People-Excitement-Obedience Medicine PEO medicine, paying attention to the coupling mechanism of "structure-behavior-function" as well as complex fluid management. Until now, he published 120 SCI papers and H factor is 27. He has initiated the formulation of two national standards for nano-imaging (Issued, GB/T 28872-2012 and GB/T 28873-2012) and has filed nine patents, five patent applications underway.

He was elected the executive board member, International Society for Clinical Haemorheology; Chairman of the Phlegm-Stasis Professional Committee, Chinese Society of Microcirculation; Member of Committee of Experts on Instrument Development of Chinese Academy of Sciences.

Research Interests:

Research Interests

Nanobiomedical Imaging and Characterization, Biomechanopharmacology

Selected Publications

1. A "green pathway" different from simple diffusion in soft matter: Fast molecular transport within micro/nanoscale multiphase porous systems, Nano Research, 2014, 3, 434-442.

2. An in vivo study of the biodistribution of gold nanoparticles after intervaginal space injection in the tarsal tunnel, Nano Research, 2016, 7, 2097-2109.

3. Flow behavior of liquid metal in the connected fascial space: Intervaginal space injection in the rat wrist and mice with tumor, Nano Research, 2018, 4, 2265-2276.

4. AuNP–Collagen Matrix with Localized Stiffness for Cardiac-Tissue Engineering: Enhancing the Assembly of Intercalated Discs by 1-Integrin-Mediated Signaling, Advanced Materials, 2016, 46, 10230–10235.

5. Adhesion Anisotropy Substrate with Janus Micropillar Arrays Guides Cell Polarized Migration and Division Cycle, Angewandte Chemie International Edition, 2019, 13, 4308–4312.

6. Bio-Inspired Hierarchical Macromolecule–Nanoclay Hydrogels for Robust Underwater Superoleophobicity, Advanced Materials,2010, 43, 4826–4830.

7. Chinese medicine, flowing blood,biomechanopharmacology and future preventive medicine, Chinese Science Bulletin,2012, 27, 3541-3546.

8. Antiplatelet and Thermally Responsive Poly(N-isopropylacrylamide) Surface with Nanoscale Topography, Journal of the American Chemical Society, 2009,131(30),10467-10472.

9. Flow behavior of liquid metal in the connected fascial space: Intervaginal space injection in the rat wrist and mice with tumor, Nano Research 2018,11(4),2265-2276.