National Center for Nanoscience and Technology, China

Faculty

Lei WANG

Title：	Professor
E-mail：	wanglei@nanoctr.cn
Affiliation：	National Center for Nanoscience and Technology (NCNST） No.11 Beiyitiao Zhongguancun, 100190 Beijing, P. R. China
Group Webpage：	http://sourcedb.nanoctr.cas.cn/zw/zxrck/201404/t20140418_4093422.html

Education and Professional Experience:

1998.09-2002.07 Bachelor of Science in Chemistry, Northeast Normal University, China

2002.09-2005.07 Master of Science in Analytical Chemistry, Northeast Normal University, China

2005.09-2008.08 Ph.D. in Polymer Nano-Engineering, Chonbuk National University, South Korea

2008.08-2009.08 Postdoctoral Researcher, Polymer BIN Fusion Research Center, Chonbuk National University, South Korea

2009.12-2012.02 Lecturer, School of Materials Science and Engineering, University of Science and Technology Beijing, China

2012.03-2014.03 Assistant Professor, Laboratory of Nanobiology and Safety Effects, National Center for Nanoscience and Technology, China

2014.03-2017.03 Associate Professor, Laboratory of Nanobiology and Safety Effects, National Center for Nanoscience and Technology, China

2017.03-2021.03 Distinguished Professor, Laboratory of Nanobiology and Safety Effects, National Center for Nanoscience and Technology, China

2017.09-2018.02 Visiting Scholar, School of Medicine, University of California, Davis, USA

2021.03-Present Full Professor, Laboratory of Nanobiology and Safety Effects, National Center for Nanoscience and Technology, China

Research Interests:

Research Interests

Process-Biomimetic Fibrogenesis

1. Ligand-receptor interaction induced transformation and self-amplifying self-assembly

2. Recognition, capture, and theranostics strategy

Selected Publications (full list via Researchgate)

1. Lu Zhang#, Di Jing#, Nian Jiang, Tatu Rojalin, Christopher Michael Baehr, Dalin Zhang, Wenwu Xiao, Yi Wu, Zhaoqing Cong, Jian Jian Li, Yuanpei Li, Lei Wang* and Kit S Lam*, Transformable Peptide Nanoparticles Arrest HER2 Signaling and Cause Cancer Cell Death In Vivo, Nature Nanotech., 2020, 15, 145-153.

2. Pei-Pei Yang#, Kuo Zhang#, Ping-Ping He, Yu Fan, Zi-Ming Chen, Da-Yong Hou, Yuan Li, Yu Yi, Dong-Bing Cheng, Jing-Ping Zhang, Lei Wang* and Hao Wang*, A Biomimetic Platelet Based on Assembling Peptides Initiates Artificial Coagulation, Sci. Adv., 2020, 6(22), eaaz4107.

3. Yu Fan#, Xiang-Dan Li#, Ping-Ping He, Xiao-Xue Hu, Kuo Zhang, Jia-Qi Fan, Pei-Pei Yang, Hao-Yan Zheng, Wen Tian, Zi-Ming Chen, Lei Ji, Hao Wang and Lei Wang*, A Biomimic Peptide Recognizes and Traps Bacteria In Vivo as Human Defensin-6, Sci. Adv., 2020, 6(19), eaaz4767.

4. Ping-Ping He#, Xiang-Dan Li#, Jia-Qi Fan, Yu Fan, Pei-Pei Yang, Bing-Nan Li, Yong Cong, Chao Yang, Kuo Zhang, Zi-Qi Wang, Da-Yong Hou, Hao Wang and Lei Wang*, Live Cells Process Exogenous Peptide as Fibronectin Fibrillogenesis, In Vivo, CCS Chem., 2020, 2(5), 539-554.

5. Kuo Zhang#, Pei-Pei Yang#, Ping-Ping He, Shi-Fang Wen, Xiao-Ran Zou, Yu Fan, Zi-Ming Chen, Hui Cao*,, Zhou Yang, Kai Yue, Xinxin Zhang, Hua Zhang, Lei Wang* and Hao Wang*, Peptide-Based Nanoparticles Mimic Fibrillogenesis of Laminin in Tumor Vessels for Precise Embolization, ACS Nano, 2020, 14(6), 7170-7180.

6. Lu Wang, Yulin Lv, Cong Li, Guang Yang, Bo Fu, Qiang Peng, Lingrui Jian, Dayong Hou, Jiaqi Wang, Changhao Zhao, Peipei Yang, Kuo Zhang, Lei Wang*, Ziqi Wang*, Hao Wang* and Wanhai Xu*, Transformable Dual-Inhibition System Effectively Suppresses Renal Cancer Metastasis through Blocking Endothelial Cells and Cancer Stem Cells, Small, 2020, 16(40), 2004548.

7. Ping-Ping He, Xiang-Dan Li*, Lei Wang* and Hao Wang*, Bispyrene-Based Self-Assembled Nanomaterials: In Vivo Self-Assembly, Transformation, and Biomedical Effects, Acc. Chem. Res., 2019, 52(2), 367-378.

8. Li-Li Li, Zeng-Ying Qiao*, Lei Wang* and Hao Wang*, Programmable Construction of Peptide-Based Materials in Living Subjects: From Modular Design and Morphological Control to Theranostics, Adv. Mater., 2019, 31(45), 1804971.

9. Yang Yang#, Lei Wang#, Hongqian Cao, Mingjuan Han, Yue Li, Hao Wang*, Bingbing Sun and Junbai Li*, Photodynamic Therapy with Liposomes Encapsulating Photosensitizers with Aggregation-Induced Emission, Nano Lett., 2019, 19(3), 1821-1826.

10. Qiang Luo#, Yao-Xin Lin#, Pei-Pei Yang#, Yi Wang, Guo-Bin Qi, Zeng-Ying Qiao, Bing-Nan Li, Kuo Zhang, Jing-Ping Zhang*, Lei Wang* and Hao Wang*, A Self-destructive Nanosweeper that Captures and Clears Amyloid β-Peptides, Nature Commun., 2018, 9, 1802.